The second season takes place one-and-a-half years after the first season. Having learned the true nature of the Sibyl System, Akane Tsunemori chose to obey the system, believing in both humanity and the legal order. She's part of a new police section and spends her everyday life facing down criminals. Unbeknownst to Akane, however, a monster who will shake the system to its core is about to appear before her.

Third film of the Mardock Scramble series. Rune Balot goes to a casino connected to the October corporation to try to wrap up her case once and for all.

承受着残酷命运的少女露恩•芭洛特（林原惠美 配音）与强敌鲍伊德（矶部勉 配音）进行着实力悬殊的惨烈战斗，危急时刻，号称万能兵器的犯罪搜查官乌夫库克博士（八岛智人 配音）出现，拯救了濒临死亡的芭洛特。当芭洛特再次醒来，发现自己正置身于传说中的禁忌科学诞生之地——“乐园”实验室，再次她见识了许多奇怪的发明，并了解到“乐园”和三博士的过去。经过一番追查，她终于得知榭尔（中井和哉 配音）的记忆正藏在卡西诺赌场的一枚筹码之中。为了追查榭尔的过去，芭洛特化装成赌客走入凶险的赌场…… 本片根据冲方丁的科幻小说改编，为“壳中少女”三部曲中第二部（另两部分别为“压缩”和“排气”）。

Rune Ballot is a down-and-out teen prostitute in Mardock City. One day, she's picked up by an ambitious casino manager named Shell who gives her everything she could want. Renewed by a false innocence, a false past, and now the false life Shell has given her, Ballot feels grateful. However, she can't help but be curious about why he's done so much for her, so she does some research about his past on a computer. This turns out to be a mistake which will change her life greatly. When Shell finds out what she's done, he attempts to burn her to death by blowing up her car.