该剧由《天使调查团》的一对制片组合Jim Kouf、David Greenwalt打造。 该剧根据《格林童话》中的原型人物和故事改编，剧中的故事和角色大多出自书中的角色。 波特兰警局警察Nick Burkhardt（大卫·君图力 David Giuntoli 饰）刚刚被 晋升为命案侦探，正准备在新的工作岗位上大展拳脚，可是他开始见到一些根本不能用言语来解释的可怕景象。Nick的姑姑Marie向Nick透露了一个惊天秘密，Nick的生活从此改变。Marie称Burkhardt家族的祖先曾隶属于一个猎人集团，他们的统一代号为“格林”。这个世界中存在大量的超自然生物，它们试图侵占世界、毁灭人类，而“格林”的任务就是阻止它们的阴谋。当Nick对家族背景有了更多了解后，越来越意识到自己对“格林”的义务责无旁贷。格林兄弟是假的，但格林童话是真的－－这个新发现不仅会影响Nick的命运，也将影响人类的命运......

Nick is being reunited with his mother, Kelly Burkhardt briefly. Sean Renard wakes Juliette from her coma with a potion, revealing himself to be a half-Zauberbiest and a Royal. The potion is causing Sean and Juliette to become dangerously obsessed with each other. This requires all of Rosalee's apothecary skills to resolve. Juliette is unable to remember her relationship with Nick. Nick is forced to explain to Hank about Wesen and that he is a Grimm. Adalind conducts affairs with both Sean Renard and his brother, Eric, to become pregnant and trading the baby with Stefania Vaduva Popescu, the Queen of the Schwarzwald Gypsies, for the return of her powers. Eric conceives a plan to capture Nick and force Sean to return to Europe using the zombies of Baron Samedi to create chaos in Portland. The season ends with Nick in a coffin in the first stage of a Cracher-Mortel victim: paralysis with a death-like appearance.

Under the effects of the Cracher-Mortel toxin, Nick causes the plane carrying him to Europe to crash, killing Baron Samedi. A residual effect of the Cracher-Mortel toxin, however, causes Nick's endurance to be increased along with his strength. Juliette, with her new-found knowledge of the Wesen world, enthusiastically joins Nick, Hank, Monroe, and Rosalee in their adventures. Adalind's pregnancy continues as she goes through the Contaminatio Ritualis with the help of Stefania, and Captain Renard realizes that the rumored royal baby being offered for sale could be Adalind's. Captain Renard arranges for the assassination of his half brother, Eric, who is replaced in the royal hierarchy by his cousin, Viktor. Monroe proposes to Rosalee, and she happily accepts.

Nick, Juliette, Hank, and Trubel go straight to Nick's home from Monroe and Rosalee's wedding after Trubel tells them that Captain Renard was shot, despite everyone being in shock that Nick has lost his Grimm powers. While Nick is powerless, he uses Trubel in Wesen cases. Nick and Juliette consider living a normal life together instead of Nick trying to get his Grimm powers back, but Juliette tells Nick he needs to get his powers back. Trubel decides Nick doesn't need her as much after he gets his powers back, so she decides to go to Philadelphia with Josh Porter. Monroe is kidnapped to have his fate decided by a tribunal for his marriage to Rosalee, as well as befriending a Grimm. Monroe is found guilty and sentenced to death, but he is saved by Nick and the gang. Soon after Nick gets his powers back, Juliette turns into a Hexenbiest as a side effect. She decides to try to get rid of it instead of telling Nick.

康斯坦丁，一个现实主义者，他很少使用魔法，用大脑和盟友解决问题，可是在他眼中盟友只是利用的对象，无论什么时候伴随他的只有死亡，他身后永远都紧随着那些因他死去的盟友们。 他厌恶那些穿着紧身衣的英雄，同样那些英雄们也厌恶着他。但他总是有一种领导力，领导那些英雄们无法判断的难题。 他欺骗魔鬼，欺骗上帝，他只为了自己，但是他有底线和原则，他自己衡量邪恶与正义。 他总是不由自主的去调戏盟友们，总会有人死心塌地的中招，然后被他伤透心。 从某种程度上讲他有很强的控制欲，当盟友不在信任他时，他会使用自己的小手段去控制住他们。 总而言之，他是一个欺诈师，心理学家，侦探，魔法师，音乐家，一个孤独的人