In the future, an outbreak of canine flu leads the mayor of a Japanese city to banish all dogs to an island used as a garbage dump. The outcasts must soon embark on an epic journey when a 12-year-old boy arrives on the island to find his beloved pet.

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Cowboy and Indian's only wish was to come up with a brilliant idea for Mr Horse's birthday, but when their plan ends up in utter disaster, they'll need to travel the world and back to make things right again.