When vengeful General Francis X. Hummel seizes control of Alcatraz Island and threatens to launch missiles loaded with deadly chemical weapons into San Francisco, only a young FBI chemical weapons expert and notorious Federal prisoner have the skills to penetrate the impregnable island fortress and take him down.

Yuri Orlov is a globetrotting arms dealer and, through some of the deadliest war zones, he struggles to stay one step ahead of a relentless Interpol agent, his business rivals and even some of his customers who include many of the world's most notorious dictators. Finally, he must also face his own conscience.

In order to foil a terrorist plot, an FBI agent undergoes facial transplant surgery and assumes the identity of a criminal mastermind. The plan turns sour when the criminal wakes up prematurely and seeks revenge.