Don Pablo Salazar steals a fortune in jewels from an Indian tribe and an Aztec medicine man puts a curse on the jewels until they are returned. Years later, an American insurance man promises to deliver the Salazar fortune to the rightful heir...

When the incompetent Lieutenant Frank Drebin seeks the ruthless killer of his partner, he stumbles upon an attempt to assassinate Queen Elizabeth II.

Unlike their heroic counterparts on the force, desk-bound NYPD detectives Gamble and Hoitz garner no headlines as they work day to day. When a seemingly minor case turns out to be a big deal, the two cops get the opportunity to finally prove to their comrades that they have the right stuff.