Tom's new book on "how to catch a mouse" doesn't prove too helpful against Jerry; actually, Jerry seems to make better use of it than Tom.

Tom is living the life of luxury, high atop a fancy apartment building. Jerry is starving way down below when he spots a lunchbox on a girder at a construction site. Jerry goes in, the girder goes up, and the lunchbox falls off, landing on Tom, and the chase is on.

宁静祥和的一天，女主人前后左右打扫卫生，忙碌不停，而汤姆则悠哉悠哉地躺在地板上地板上睡大觉，全然不将女主人放在眼里。另一边，小老鼠杰瑞大摇大摆将奶酪搬回窝里，汤姆连看都懒得看。主人似乎对他彻底失望了，全然不怒。这时门铃声响起，快递送来了女主人期盼已久的物品——Mechano机器猫，不用喂食，不会烦人，也全无杂毛，干净高效。从现在起，它将代替汤姆承担捉老鼠的工作。机器猫不负众望，轻松抓到杰瑞将其赶了出去，气馁的汤姆只得拿着行李离开。 但是如临大敌的杰瑞决不会允许这种事情发生，他必须和汤姆联合起来……

在玩具随意摆放的房间里，小女孩南希正大声斥责躲在角落里的汤姆，她把汤姆当作一个不听话的小娃娃，甚至还把他抓出来包上尿布塞到婴儿床内。面对这个专横跋扈的小主人，平时耀武扬威的汤姆也没了脾气，只得任由南希摆布。突然，他发现南希塞过来的奶瓶里的奶水分外好喝，于是这个馋嘴的家伙干脆卖乖装起婴儿，大喝奶水，还摆出各种幼稚的动作。这一切都被小老鼠杰瑞看在眼里，他大声嘲笑汤姆，并模仿他的动作，惹得汤姆恼羞成怒。一场猫鼠大战就这样爆发了…… 本片是动画人Ray Patterson从迪斯尼过档华纳后参与制作的首部Tom & Jerry系列动画片。

Jerry's little duckling friend is depressed because he's just read The Ugly Duckling and thinks that he's ugly. Jerry does his best to help. Tom gets involved when the suicidal duck offers himself as a meal.

夜幕降临，寂静的社区内，一所大房子里传来了吵闹声。原来汤姆正在追赶小老鼠杰瑞，结果打破了许多器皿，令女主人非常生气。主人责令他打扫碎片，汤姆虽然心又不满，可还是气鼓鼓地打扫起来。这时，桌子上一份报纸的招募启事引起了他的兴趣。启事写道寻找一个志愿者和老妇人环游世界。对汤姆来说，这可真是一个摆脱现有枯燥生活的好机会。他扔掉手中的扫帚和簸箕，夹着报纸前去应聘。 谁知，应聘的地点竟然是一桩破烂阴森的古堡，而所谓的老妇人竟然是一名长相丑陋的巫婆。虽然想转身逃跑，可是老巫婆根本不容他拒绝，便带着汤姆飞上了天空……

伴随着巨大的轰鸣声，一颗人造卫星发射到了外太空，它的目的地是那个宛如巨大轮盘赌的一号空间站。卫星里载满了供宇航员们日常所用的物资。传送带将物资缓缓运入舱内，其中包含一枚巨大的奶酪，这引起了空间站内另一名住客——小老鼠杰瑞的兴趣。他随即动身窃取奶酪，无意中触发了警报系统。老猫汤姆是空间站的警卫，他从监控屏上看到了杰瑞，随即命令机器猫前去拦截。谁知机器猫遭到杰瑞的戏耍，反过来给汤姆带来巨大的麻烦。 无奈之下，汤姆只得亲自上阵，他找来超级强大的激光枪，和小老鼠在空间站内展开一场超现实的星球大战……

这一天，小老鼠杰瑞收到叔叔佩克斯的电报，他这位住在得州的叔叔将带着心爱的吉他来到杰瑞的住处看电视，并作短暂停留。看到电报后杰瑞非常高兴，这时敲门声响起，带着牛仔帽、穿马靴、留了两簇浓密白胡子的叔叔走进房间，自顾自地为侄子弹唱起来。谁知唱到高潮处时，琴弦突然断掉。叔叔竟然走进房间，从正在睡觉的汤姆脸上揪了一根胡子下来当琴弦。杰瑞想方设法阻止叔叔的疯狂举动，但三番五次过后，汤姆却怕起了这个混不吝的老鼠叔叔。他四处躲藏，可是总也无法逃避胡子被揪掉的命运。 杰瑞叔叔到来，无疑是汤姆的前所未有的噩梦……

在一个阳光明媚、海风轻柔的美好日子里，巨型邮轮停靠在码头旁边装运货物。木箱子中的奶酪香气诱人，引得熟睡中的杰瑞神魂颠倒，无法自持。他固然想要冲上船去饱餐一顿，可是舷梯前全副武装的汤姆正在来回走动巡逻，难以靠近。杰瑞灵机一动，从洞内找来船长的帽子和衣服，顶着这身行头走上舷梯。他的小把戏自然不会逃过汤姆毒辣的眼睛，汤姆将舷梯推开，结果杰瑞掉落海中，还险些被大鲨鱼当成点心。杰瑞下的面色惨白，而汤姆则得意地哈哈大笑。可是，船长也不慎从没有舷梯的船上掉了下来，汤姆也变得手忙脚乱…… 本片是汤姆和杰瑞系列中Chuck Jones担任制作人和Carl Brandt担任配乐的首部作品。

Tom chases Jerry through city streets, gets run over by a streetcar (twice), and follows Jerry into a department store. In the toy department, they have some fun with radio-controlled cars and a collection of mouse dolls. They move on to sporting goods, where Jerry manages to combine table tennis with croquet.

阳光多么明媚的一天，如果能逍遥自在度过该多好。可是汤姆和杰瑞这对冤家似乎从来不知该如何享受生活，他们辜负了大好的阳光，在房间内展开了疯狂的追逐战。两个小家伙的速度越来越快，俨然变成了飞驰的跑车。结果汤姆来不及刹车，狠狠地撞在墙上，变成了板凳。稍后他打算把墙锯断，最终弄巧成拙，被倒塌的墙拍在下面。追逐战再度开始，谁知杰瑞好像跑圈一样，一遍遍从汤姆身后超过，令老猫大为诧异。少顷，他们的战斗移到户外，竟然在高楼大厦的窗户外追杀起来。 惊险的场面接二连三发生，这两个不要命的小家伙啊……

Jerry narrates in voiceover: Tom has fallen hard for the cat next door, and competes with rich cat Butch for her affections. But Butch outspends Tom to a ludicrous level at every turn. Tom goes downhill after that, until we see him contemplating suicide.

Tom steals an egg from a mother duck's nest, but soon the resultant hatchling runs away from the cat and into a mouse hole, where it finds an able protector in Jerry.

At the home of Viennese composer Johann Strauss lived Johann Mouse. Whenever the composer played his waltzes, the mouse would dance to the music, unable to control himself. One day, when Strauss was away, the house cat played his master's music. When word got out about a piano-playing cat and a dancing mouse, they were commanded to perform for the emperor.

Tom chases Jerry into a fish cannery; they get sealed into cans. Tom breaks out, but falls off a pier as the cans roll under him. A shark chases him out of the water; Tom drops an anchor on the shark. Meanwhile, Jerry has been hopping in his can; Tom opens it, and puts his finger in, which Jerry bites. Jerry tricks Tom into falling off the end of another pier, and right into the shark's path again. The shark manages to get Tom into a very precarious position, barely holding the jaws apart. Jerry takes pity, and dumps a shaker full of pepper into the shark, which ends up on the processing line and stuffed into a huge can. Tom is unrepentant, so Jerry tricks him with a fake shark fin.