Following the events of Age of Ultron, the collective governments of the world pass an act designed to regulate all superhuman activity. This polarizes opinion amongst the Avengers, causing two factions to side with Iron Man or Captain America, which causes an epic battle between former allies.

After his career is destroyed, a brilliant but arrogant surgeon gets a new lease on life when a sorcerer takes him under her wing and trains him to defend the world against evil.

Light years from Earth, 26 years after being abducted, Peter Quill finds himself the prime target of a manhunt after discovering an orb wanted by Ronan the Accuser.

As the Avengers and their allies have continued to protect the world from threats too large for any one hero to handle, a new danger has emerged from the cosmic shadows: Thanos. A despot of intergalactic infamy, his goal is to collect all six Infinity Stones, artifacts of unimaginable power, and use them to inflict his twisted will on all of reality. Everything the Avengers have fought for has led up to this moment - the fate of Earth and existence itself has never been more uncertain.

Just when his time under house arrest is about to end, Scott Lang once again puts his freedom at risk to help Hope van Dyne and Dr. Hank Pym dive into the quantum realm and try to accomplish, against time and any chance of success, a very dangerous rescue mission.

Investigative journalist Eddie Brock attempts a comeback following a scandal, but accidentally becomes the host of Venom, a violent, super powerful alien symbiote. Soon, he must rely on his newfound powers to protect the world from a shadowy organization looking for a symbiote of their own.

The X-Men face their most formidable and powerful foe when one of their own, Jean Grey, starts to spiral out of control. During a rescue mission in outer space, Jean is nearly killed when she's hit by a mysterious cosmic force. Once she returns home, this force not only makes her infinitely more powerful, but far more unstable. The X-Men must now band together to save her soul and battle aliens that want to use Grey's new abilities to rule the galaxy.

With David and Oliver missing and Farouk on the loose, the team forms an unlikely alliance with their former enemy Clark and his well-funded government is on a new path to attaining infinite and world-ending power.

在《X战警》漫画中，X特工队（X-Force）隶属于X战警。他们与正面形象示人的镭射眼等人不同，擅长用一些极端、残暴的方式与敌人对抗，为了保护变种人的生命勇往直前。主要成员包括金刚狼、X-23（金刚狼的克隆体）、印第安战士Warpath、具有高度飞行能力的Archange l以及拥有变身能力的Wolfsbane。据传闻称来自未来的镭射眼之子Cable和他的好友Deadpool会在电影中扮演重要角色。