From the Egyptian desert to deep below the polar ice caps, the elite G.I. JOE team uses the latest in next-generation spy and military equipment to fight the corrupt arms dealer Destro and the growing threat of the mysterious Cobra organization to prevent them from plunging the world into chaos.

Cobb, a skilled thief who commits corporate espionage by infiltrating the subconscious of his targets is offered a chance to regain his old life as payment for a task considered to be impossible: "inception", the implantation of another person's idea into a target's subconscious.

In the year 2044, time travel has not yet been invented but in 30 years it will have been. When the mob wants to get rid of someone, they will send their target into the past where a looper, a hired gun, like Joe is waiting to mop up. Joe is getting rich and life is good until the day the mob decides to close the loop, sending back Joe's future self for assassination.