In the 19th century, Dracula travels to London and meets Mina, a young woman who appears as the reincarnation of his lost love.

In the year 2019, a plague has transformed almost every human into a vampire. Faced with a dwindling blood supply, the fractured dominant race plots their survival; meanwhile, a researcher works with a covert band of vampires on a way to save humankind.

Forks, Washington resident Bella Swan is reeling from the departure of her vampire love, Edward Cullen, and finds comfort in her friendship with Jacob Black, a werewolf. But before she knows it, she's thrust into a centuries-old conflict, and her desire to be with Edward at any cost leads her to take greater and greater risks.

Bella once again finds herself surrounded by danger as Seattle is ravaged by a string of mysterious killings and a malicious vampire continues her quest for revenge. In the midst of it all, she is forced to choose between her love for Edward and her friendship with Jacob, knowing that her decision has the potential to ignite the ageless struggle between vampire and werewolf. With her graduation quickly approaching, Bella is confronted with the most important decision of her life.

A rare mutation has occurred within the vampire community - The Reaper. A vampire so consumed with an insatiable bloodlust that they prey on vampires as well as humans, transforming victims who are unlucky enough to survive into Reapers themselves. Blade is asked by the Vampire Nation for his help in preventing a nightmare plague that would wipe out both humans and vampires.

The Daywalker known as "Blade" - a half-vampire, half-mortal man - becomes the protector of humanity against an underground army of vampires.

For years, Blade has fought against the vampires in the cover of the night. But now, after falling into the crosshairs of the FBI, he is forced out into the daylight, where he is driven to join forces with a clan of human vampire hunters he never knew existed—The Nightstalkers. Together with Abigail and Hannibal, two deftly trained Nightstalkers, Blade follows a trail of blood to the ancient creature that is also hunting him—the original vampire, Dracula.

Rayne fights against the Nazis in Europe during World War II, encountering Ekart Brand, a Nazi leader whose target is to inject Adolf Hitler with Rayne's blood in an attempt to transform him into a dhampir and attain immortality.

Vlad Tepes is a great hero, but when he learns the Sultan is preparing for battle and needs to form an army of 1,000 boys, he vows to find a way to protect his family. Vlad turns to dark forces in order to get the power to destroy his enemies and agrees to go from hero to monster as he's turned into the mythological vampire, Dracula.