Deathly ill Count Dracula and his slimy underling, Anton, travel to Italy in search of a virgin's blood. They're welcomed at the crumbling estate of indebted Marchese Di Fiore, who's desperate to marry off his daughters to rich suitors. But there, instead of pure women, the count encounters incestuous lesbians with vile blood and Marxist manservant Mario, who's suspicious of the aristocratic Dracula.

A respected priest volunteers for an experimental procedure that may lead to a cure for a deadly virus. He gets infected and dies, but a blood transfusion of unknown origin brings him back to life. Now, he’s torn between faith and bloodlust, and has a newfound desire for the wife of a childhood friend.

The activities of rampaging, indiscriminate serial killer Ben are recorded by a willingly complicit documentary team, who eventually become his accomplices and active participants. Ben provides casual commentary on the nature of his work and arbitrary musings on topics of interest to him, such as music or the conditions of low-income housing, and even goes so far as to introduce the documentary crew to his family. But their reckless indulgences soon get the better of them.

The lethal Reaper virus spreads throughout Britain—infecting millions and killing hundreds of thousands. Authorities brutally and successfully quarantine the country but, three decades later, the virus resurfaces in a major city. An elite group of specialists is urgently dispatched into the still-quarantined country to retrieve a cure by any means necessary. Shut off from the rest of the world, the unit must battle through a landscape that has become a waking nightmare.