In honor of his birthday, San Francisco banker Nicholas Van Orton, a financial genius and a cold-hearted loner, receives an unusual present from his younger brother, Conrad: a gift certificate to play a unique kind of game. In nary a nanosecond, Nicholas finds himself consumed by a dangerous set of ever-changing rules, unable to distinguish where the charade ends and reality begins.

In 2003, Harvard undergrad and computer programmer Mark Zuckerberg begins work on a new concept that eventually turns into the global social network known as Facebook. Six years later, Mark is one of the youngest billionaires ever, but his unprecedented success leads to both personal and legal complications when he ends up on the receiving end of two lawsuits, one involving his former friend.

The zodiac murders cause the lives of Paul Avery, David Toschi and Robert Graysmith to intersect.