Inspired by true events, this film takes place in Rwanda in the 1990s when more than a million Tutsis were killed in a genocide that went mostly unnoticed by the rest of the world. Hotel owner Paul Rusesabagina houses over a thousand refuges in his hotel in attempt to save their lives.

Two South African boys, one white, Rhino, and one black, Zulu, go their separate ways after an incident. Many years later, they meet up again as adults, when one, after living for years in the United States, is now a wanted criminal. The two end up being a part of a madcap chase involving a check for a large amount of lottery money, pursued by Gen. Diehard and Rhino's ex-wife Rowena, who was the cause of the rift between the two protagonists.

在广袤无垠的非洲，经常有为谋取暴利的偷猎者在凶残地围捕大象…… 麦克、凯瑞和查尔斯等人在非洲旅游，被首领的儿子炔回部落，天黑后，他们逃走时击毙了首领。在葬礼上首领儿子发誓要报杀父之仇，他手拿标枪带着对部族的誓言，只身一人凭着敏锐的嗅觉，向麦克等人逃跑的方向奔去…… 该影片全部在非洲实景拍摄，风光异常壮观，涉及到非洲的河流、瀑布、森林以及全部的非洲野生动物。通过描写三位主人公位保护野生动物与偷猎者斗争的经过，表现了那些热爱动物、热爱和平的人们，位保护野生动物的事业所做的努力。