When the young Texas Ranger, John Reid, is the sole survivor of an ambush arranged by the militaristic outlaw leader, Butch Cavendich, he is rescued by an old childhood Comanche friend, Tonto. When he recovers from his wounds, he dedicates his life to fighting the evil that Cavendich represents. To this end, John Reid becomes the great masked western hero, The Lone Ranger. With the help of Tonto, the pair go to rescue President Grant when Cavendich takes him hostage.

As the west rapidly becomes civilized, a pair of outlaws in 1890s Wyoming find themselves pursued by a posse and decide to flee to South America in hopes of evading the law.