After the attempted assassination of the president, Carrie Mathison is out of the White House while 200 members of the intelligence community are imprisoned. Now Carrie must prove that not all conspiracies are theories.

The government gets wind of a plot to destroy America involving a trio of nuclear weapons for which the whereabouts are unknown. It's up to a seasoned interrogator and an FBI agent to find out exactly where the nukes are.

When the president of Russia suddenly dies, a man whose politics are virtually unknown succeeds him. The change in political leaders sparks paranoia among American CIA officials, so CIA director Bill Cabot recruits a young analyst to supply insight and advice on the situation. Then the unthinkable happens: a nuclear bomb explodes in a U.S. city, and America is quick to blame the Russians.