Immediately after the events of The Desolation of Smaug, Bilbo and the dwarves try to defend Erebor's mountain of treasure from others who claim it: the men of the ruined Laketown and the elves of Mirkwood. Meanwhile an army of Orcs led by Azog the Defiler is marching on Erebor, fueled by the rise of the dark lord Sauron. Dwarves, elves and men must unite, and the hope for Middle-Earth falls into Bilbo's hands.

Following the shocking developments at the conclusion of season five, survivors from all parts of Westeros and Essos regroup to press forward, inexorably, towards their uncertain individual fates. Familiar faces will forge new alliances to bolster their strategic chances at survival, while new characters will emerge to challenge the balance of power in the east, west, north and south.