Vampire death dealer Selene fends off brutal attacks from both the Lycan clan and the Vampire faction that betrayed her. With her only allies, David and his father Thomas, she must stop the eternal war between Lycans and Vampires, even if it means she has to make the ultimate sacrifice.

As the war between the vampires and the Lycans rages on, Selene, a former member of the Death Dealers (an elite vampire special forces unit that hunts werewolves), and Michael, the werewolf hybrid, work together in an effort to unlock the secrets of their respective bloodlines.

Having escaped years of imprisonment, vampire warrioress Selene finds herself in a changed world where humans have discovered the existence of both Vampire and Lycan clans and are conducting an all-out war to eradicate both immortal species. Now Selene must battle the humans and a frightening new breed of super Lycans to ensure the death dealers' survival.