Two homicide detectives are on a desperate hunt for a serial killer whose crimes are based on the "seven deadly sins" in this dark and haunting film that takes viewers from the tortured remains of one victim to the next. The seasoned Det. Sommerset researches each sin in an effort to get inside the killer's mind, while his novice partner, Mills, scoffs at his efforts to unravel the case.

Born under unusual circumstances, Benjamin Button springs into being as an elderly man in a New Orleans nursing home and ages in reverse. Twelve years after his birth, he meets Daisy, a child who flits in and out of his life as she grows up to be a dancer. Though he has all sorts of unusual adventures over the course of his life, it is his relationship with Daisy, and the hope that they will come together at the right time, that drives Benjamin forward.