The autonomous robot staff of the Gingarou Hotel, led by concierge Yachiyo, as they maintain the deserted hotel in a post-human Earth. After humans evacuate due to a toxic environmental contagion, the robots wait for their return, until alien guests, starting with an extraterrestrial visitor and then a family of tanuki aliens, begin to arrive. The season explores their adaptation to serving alien clients, the humorous and sometimes melancholic challenges of their duties in a world without humans, and the evolving relationships between the robot staff and their new, non-human guests.

Continuing where Stitch! The Movie left off, Lilo and Stitch are given the task of collecting the rest of Jumba's missing experiments, changing them from bad to good, and finding the one place where they truly belong. Meanwhile, the former Captain Gantu and his reluctant partner, Experiment 625, try to capture the experiments for the imprisoned Dr. Hämsterviel.
Running for two seasons and a total of 65 episodes, the series (and the franchise) ended with the direct-to-DVD movie Leroy & Stitch.
Repeats currently air on Disney Junior.