Professor Se-jeong is thrust into a bloody nightmare when a rapidly mutating virus is released during a biotech conference causing authorities to seal the facility. Trapped inside with no escape, Se-jeong along with a small group of survivors must fight to stay alive while the infected undergo horrific transformations.

It's been almost three decades since the rage virus escaped a biological weapons laboratory, and now, still in a ruthlessly enforced quarantine, some have found ways to exist amidst the infected. One such group of survivors lives on a small island connected to the mainland by a single, heavily-defended causeway. When one of the group leaves the island on a mission into the dark heart of the mainland, he discovers secrets, wonders, and horrors that have mutated not only the infected but other survivors as well.