医学
Bottle of Lies: The Inside Story of the Generic Drug Boom Douban
8.0 (9 ratings) author: Katherine Eban publishing house: Ecco 2019 - 5
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
Jan. 27, 2022 read
一个这么好的题材,被作者写得稀烂。故事非常散乱且冗长。有种所有我调查到的内容都要填进去的杂乱感。人物脸谱化,凡正面角色一定要讲到成长经历,父亲职业的影响,反面角色一定是生活奢迷,草菅人命,毫无道德可言。350字装不下我的吐槽。可能需要写一篇长评。。。。。。
英文原版 wildwestbookclub audiobook 医学 美国
The Gene Douban
8.3 (6 ratings) author: Siddhartha Mukherjee publishing house: Scribner 2016 - 5
From the Pulitzer Prize-winning, bestselling author of The Emperor of All Maladies—a magnificent history of the gene and a response to the defining question of the future: What becomes of being human when we learn to “read” and “write” our own genetic information?
The extraordinary Siddhartha Mukherjee has a written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
Throughout the narrative, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—cuts like a bright, red line, reminding us of the many questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In superb prose and with an instinct for the dramatic scene, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome.
As The New Yorker said of The Emperor of All Maladies, “It’s hard to think of many books for a general audience that have rendered any area of modern science and technology with such intelligence, accessibility, and compassion…An extraordinary achievement.” Riveting, revelatory, and magisterial history of a scientific idea coming to life, and an essential preparation for the moral complexity introduced by our ability to create or “write” the human genome, The Gene is a must-read for everyone concerned about the definition and future of humanity. This is the most crucial science of our time, intimately explained by a master.
Dec. 12, 2021 read
啃了一个月终于啃完了。很宏大的一个主题,作者深入浅出的讨论了基因的方方面面,很多很有想象力的比喻来帮助读者理解,对于基因工程带来的对于社会伦理道德的挑战又很深入的讨论。作为一本科普读物非常合格。
英文原版 科普 2021 医学
众病之王 Douban
The Emperor of All Maladies: A Biography of Cancer
9.1 (110 ratings) author: [美] 悉达多·穆克吉 translator: 李虎 publishing house: 中信出版社 2013 - 2
《众病之王:癌症传》是一部饱含人文主义色彩的社科文化著作。作者悉达多•穆克吉历时六年,凭借翔实的历史资料、专业文献、媒体报道、患者专访等众多信息,向读者阐述了癌症的起源与发展,人类对抗癌症、预防癌症的斗争史。作者借由医学、文化、社会、政治等视角透露出一种社会化关怀;生动、文学性的写作手法展现出鲜活的人物和历史事件,让读者为之动容。
Sept. 15, 2021 read
五星推荐,预定年度最佳。基础数据翔实,深入浅出,引人入胜!是那种如果我再年轻十年会inspire我去学生物的好书!
科学 疾病 科普 健康 westwildbookclub
The Body Douban Goodreads Skybridge Skybridge
The Body: A Guide for Occupants
7.5 (6 ratings) author: [美] 比尔·布莱森 publishing house: Doubleday 2019 - 10 other title: The Body A Guide for Occupants / The Body: A Guide for Occupants
Bill Bryson, bestselling author of A Short History of Nearly Everything, takes us on a head-to-toe tour of the marvel that is the human body. As addictive as it is comprehensive, this is Bryson at his very best, a must-read owner's manual for everybody.
Bill Bryson once again proves himself to be an incomparable companion as he guides us through the human body--how it functions, its remarkable ability to heal itself, and (unfortunately) the ways it can fail. Full of extraordinary facts (your body made a million red blood cells since you started reading this) and irresistible Bryson-esque anecdotes, The Body will lead you to a deeper understanding of the miracle that is life in general and you in particular. As Bill Bryson writes, "We pass our existence within this wobble of flesh and yet take it almost entirely for granted." The Body will cure that indifference with generous doses of wondrous, compulsively readable facts and information.
Nov. 30, 2020 read
#audiobook Bill Bryson是我心中的大神,之前写的关于澳洲那本觉得是又有趣知识点又多。这本the body关于人体器官简述的书刚出的时候就很想听又是专业相关!但是没想到!!!是作者自己读的,无比平缓的语速让人昏昏欲睡,内容也乏善可陈,就是无趣的数字堆积,简直可以又名那些年人类对自己身体做过的蠢事!全书全长14时4分 听到大概12小时的时候实在是再也听不进去了!希望Bill Bryson自己再也不要读自己写的书了,简直就是糟蹋和浪费!2020年读书时长150时 16分
英文原版 非虚构 医学 audiobook
When Breath Becomes Air Douban Goodreads
8.8 (33 ratings) author: Paul Kalanithi publishing house: Random House 2016 - 1
For readers of Atul Gawande, Andrew Solomon, and Anne Lamott, a profoundly moving, exquisitely observed memoir by a young neurosurgeon faced with a terminal cancer diagnosis who attempts to answer the question What makes a life worth living?
At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated. When Breath Becomes Air chronicles Kalanithi’s transformation from a naïve medical student “possessed,” as he wrote, “by the question of what, given that all organisms die, makes a virtuous and meaningful life” into a neurosurgeon at Stanford working in the brain, the most critical place for human identity, and finally into a patient and new father confronting his own mortality.
What makes life worth living in the face of death? What do you do when the future, no longer a ladder toward your goals in life, flattens out into a perpetual present? What does it mean to have a child, to nurture a new life as another fades away? These are some of the questions Kalanithi wrestles with in this profoundly moving, exquisitely observed memoir.
Paul Kalanithi died in March 2015, while working on this book, yet his words live on as a guide and a gift to us all. “I began to realize that coming face to face with my own mortality, in a sense, had changed nothing and everything,” he wrote. “Seven words from Samuel Beckett began to repeat in my head: ‘I can’t go on. I’ll go on.’” When Breath Becomes Air is an unforgettable, life-affirming reflection on the challenge of facing death and on the relationship between doctor and patient, from a brilliant writer who became both.
Nov. 10, 2020 read
#audiobook 斯坦福7年级前途无量的神经科手术师的自传,他前途一片大好的时候发现自己患有肺癌,与之抗争最后不幸英年早逝。书并没有写完作者就过世了,有夫人写的后记让人潸然泪下,听完容易让人depressing,并没有我想象中的很多对于死亡与生命思考。时长5小时35分。2020年度听书累计时长122时52分
audiobook 死亡 传记 癌症 美国