非虚构
Empire of Pain Douban Goodreads
Empire of Pain: The Secret History of the Sackler Dynasty
9.4 (15 ratings) author: Patrick Radden Keefe publishing house: Doubleday 2021 - 4
A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin, by the prize-winning, bestselling author of Say Nothing
The Sackler name adorns the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis.
Empire of Pain begins with the story of three doctor brothers, Raymond, Mortimer and the incalculably energetic Arthur, who weathered the poverty of the Great Depression and appalling anti-Semitism. Working at a barbaric mental institution, Arthur saw a better way and conducted groundbreaking research into drug treatments. He also had a genius for marketing, especially for pharmaceuticals, and bought a small ad firm.
Arthur devised the marketing for Valium, and built the first great Sackler fortune. He purchased a drug manufacturer, Purdue Frederick, which would be run by Raymond and Mortimer. The brothers began collecting art, and wives, and grand residences in exotic locales. Their children and grandchildren grew up in luxury.
Forty years later, Raymond’s son Richard ran the family-owned Purdue. The template Arthur Sackler created to sell Valium—co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness—was employed to launch a far more potent product: OxyContin. The drug went on to generate some thirty-five billion dollars in revenue, and to launch a public health crisis in which hundreds of thousands would die.
This is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful.
Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling. It is a portrait of the excesses of America’s second Gilded Age, a study of impunity among the super elite and a relentless investigation of the naked greed and indifference to human suffering that built one of the world’s great fortunes.
March 19, 2022 read
写了我非常喜欢的say nothing 的调查型作家Patrick Keefe去年的新书。非常详实的讲述了oxycontin的发家史。相当精彩。没想到我们这么常用的止痛药,在美国乃至全世界造成了这么严重的鸦片类药物滥用。有一个有趣的小知识居然是因为sterotype严重,医生不愿意给Africa-american开鸦片类药物的处方,结果黑人居然是最少滥用的人群。所以从一个侧面也说明,如果从处方严格管理控制,也是有效的吧。希望会有更多的RCT的结论。有声书由作者自己讲述,讲得还是非常精彩的。用词简单,情节丰富,非常推荐。时长18时7时。
医药行业 非虚构 英文原著 audiobook
The Body Douban Goodreads Skybridge Skybridge
The Body: A Guide for Occupants
7.5 (6 ratings) author: [美] 比尔·布莱森 publishing house: Doubleday 2019 - 10 other title: The Body A Guide for Occupants / The Body: A Guide for Occupants
Bill Bryson, bestselling author of A Short History of Nearly Everything, takes us on a head-to-toe tour of the marvel that is the human body. As addictive as it is comprehensive, this is Bryson at his very best, a must-read owner's manual for everybody.
Bill Bryson once again proves himself to be an incomparable companion as he guides us through the human body--how it functions, its remarkable ability to heal itself, and (unfortunately) the ways it can fail. Full of extraordinary facts (your body made a million red blood cells since you started reading this) and irresistible Bryson-esque anecdotes, The Body will lead you to a deeper understanding of the miracle that is life in general and you in particular. As Bill Bryson writes, "We pass our existence within this wobble of flesh and yet take it almost entirely for granted." The Body will cure that indifference with generous doses of wondrous, compulsively readable facts and information.
Nov. 30, 2020 read
#audiobook Bill Bryson是我心中的大神,之前写的关于澳洲那本觉得是又有趣知识点又多。这本the body关于人体器官简述的书刚出的时候就很想听又是专业相关!但是没想到!!!是作者自己读的,无比平缓的语速让人昏昏欲睡,内容也乏善可陈,就是无趣的数字堆积,简直可以又名那些年人类对自己身体做过的蠢事!全书全长14时4分 听到大概12小时的时候实在是再也听不进去了!希望Bill Bryson自己再也不要读自己写的书了,简直就是糟蹋和浪费!2020年读书时长150时 16分
英文原版 非虚构 医学 audiobook
The Hot Zone Douban
8.2 (9 ratings) author: Richard Preston publishing house: Bantam Doubleday Dell Publishing Group 1995 - 7
A highly infectious, deadly virus from the central African rain forest suddenly appears in the suburbs of Washington, D.C. There is no cure. In a few days 90 percent of its victims are dead. A secret military SWAT team of soldiers and scientists is mobilized to stop the outbreak of this exotic "hot" virus. The Hot Zone tells this dramatic story, giving a hair-raising account of the
appearance of rare and lethal viruses and their "crashes" into the human race. Shocking, frightening, and impossible to ignore, The Hot Zone proves that truth really is scarier than fiction.