Clarice Starling is a top student at the FBI's training academy. Jack Crawford wants Clarice to interview Dr. Hannibal Lecter, a brilliant psychiatrist who is also a violent psychopath, serving life behind bars for various acts of murder and cannibalism. Crawford believes that Lecter may have insight into a case and that Starling, as an attractive young woman, may be just the bait to draw him out.

William Parrish, media tycoon, loving father, and still a human being, is about to celebrate his 65th birthday. One morning, he is contacted by the inevitable, by hallucination, as he thinks. Later, Death enters his home and his life, personified in a man's body: Joe Black has arrived. His intention was to take William with him, but accidentally, Joe's former host and William's beautiful daughter Susan have already met. Joe begins to develop certain interest in life on Earth, as well as in Susan, who has no clue with whom she's flirting.