Ryūji Takasu is a gentle high school student with a love for housework; but in contrast to his kind nature, he has an intimidating face that often gets him labeled as a delinquent. On the other hand is Taiga Aisaka, a small, doll-like student who is anything but a cute and fragile girl. Equipped with a wooden katana and feisty personality, Taiga is known throughout the school as the "Palmtop Tiger." One day, an embarrassing mistake causes the two students to cross paths. Ryūji discovers that Taiga actually has a sweet side: she has a crush on the popular vice president, Yūsaku Kitamura, who happens to be his best friend. But things only get crazier when Ryūji reveals that he has a crush on Minori Kushieda—Taiga's best friend! Toradora! is a romantic comedy that follows this odd duo as they embark on a quest to help each other with their respective crushes, forming an unlikely alliance in the process.

塔原直哉（佐藤利奈 配音）是一名单身父亲，独自抚养着女儿明日叶（田村由加莉 配音）。某日，直哉在求职的途中遇见了一名神秘女子，这位女子竟然施展魔法将直哉传送到了由梦魔族统治的尤各瓦尔兰王国中。 露蒂（钉宫理惠 配音）是王国的公主，依靠吸收男性的精气维生，然而，童年的意外遭遇让露蒂对男性充满了厌恶，而直哉则成为了她的后宫，随时待命准备侍奉露蒂。起初，露蒂只是将直哉视作派遣无聊的玩具，然而，随着时间的推移，直哉的善良渐渐吸引了露蒂，露蒂的心中竟然生出了对于直哉的好感。让直哉没有想到的是，女儿明日叶亦被传送到了王国之中，露蒂就此交上了人生的第一个朋友。