本集根据《波西米亚丑闻》改编。正当 莫里亚提和夏洛克处于生死相搏之时，莫里亚提的手机响了，他接到了一个神秘的电话，不得不放弃和 夏洛克的博弈，而电话的另一头，一个妖娆女人的手出现在画面中，她手上似乎掌握着莫里亚提十分想要的东西。

The quirky spin on Conan Doyle's iconic sleuth pitches him as a "high-functioning sociopath" in modern-day London. Assisting him in his investigations: Afghanistan War vet John Watson, who's introduced to Holmes by a mutual acquaintance.