Retired from active duty, and training recruits for the Impossible Mission Force, agent Ethan Hunt faces the toughest foe of his career: Owen Davian, an international broker of arms and information, who is as cunning as he is ruthless. Davian emerges to threaten Hunt and all that he holds dear -- including the woman Hunt loves.

When an IMF mission ends badly, the world is faced with dire consequences. As Ethan Hunt takes it upon himself to fulfill his original briefing, the CIA begin to question his loyalty and his motives. The IMF team find themselves in a race against time, hunted by assassins while trying to prevent a global catastrophe.

Ethan and team take on their most impossible mission yet—eradicating 'The Syndicate', an International and highly-skilled rogue organization committed to destroying the IMF.

With computer genius Luther Stickell at his side and a beautiful thief on his mind, agent Ethan Hunt races across Australia and Spain to stop a former IMF agent from unleashing a genetically engineered biological weapon called Chimera. This mission, should Hunt choose to accept it, plunges him into the center of an international crisis of terrifying magnitude.