Hellboy comes to England, where he must defeat Nimue, Merlin's consort and the Blood Queen. But their battle will bring about the end of the world, a fate he desperately tries to turn away.

Picking up immediately after the events in Resident Evil: Retribution, Alice is the only survivor of what was meant to be humanity's final stand against the undead. Now, she must return to where the nightmare began - The Hive in Raccoon City, where the Umbrella Corporation is gathering its forces for a final strike against the only remaining survivors of the apocalypse.