Our two genius roommates, Leonard and Sheldon, and their friends are back once again (smarter, but no wiser). Last season, Sheldon went soul-searching (on a train, of course) and was prepared to make some substantial revisions on his Relationship Agreement with Amy, when everything changed. Leonard, meanwhile, was off to Vegas with Penny to finally tie the knot in the season finale. Howard finds himself alone with Bernadette after the sudden passing of his mother; while Raj is not only talking to women – he’s getting exclusive with Emily. Together, they will all learn that life is far more complicated outside of the lab as love and friendship never produce predictable results!

Whether on or above Earth, hilarity is outrageously universal in TV's most popular comedy featuring four forward-thinking but socially backward geniuses. Fun discoveries multiply: Leonard learns jealousy is bad for a relationship (with Penny) but science is good for seduction (of Penny). Howard finds life in the International Space Station life is no escape from terrestrial turmoil between his mom and his new wife Bernadette. Raj meets someone special who may be a good match, if he can keep her from fleeing mid-date. And then there's Sheldon. He learns what not to say after facing harassment charges or competing for tenure at work and how Dungeons & Dragons can be the icebreaker his relationship with Amy needs.

In season five, Penny and Leonard's relationship is relaunched in full "beta test" mode, while Sheldon, Howard, and Raj discover the feminine mystique is something that cannot be easily graphed or calculated. As Sheldon makes begrudging amendments to his "Relationship Agreement" with his "friend-who-happens-to-be-a-girl" Amy Farrah Fowler, Raj contemplates an arranged marriage, and Howard is all-systems-go for both is NASA space launch and wedding to the spirited Bernadette.

This season the Big Bang gang’s romantic universe expands. On the rebound from Penny, Leonard falls into the arms of Raj’s sister Priya. Sheldon gets a girlfriend, or rather a friend who is a girl: Amy, a dour neurobiologist who declares herself besties with Penny. Howard and Bernadette heat up. And so do Raj and Bernadette (at least in Raj’s Bollywood daydream).