The Instant New York Times best seller! Riveting. ... [Marsh] gives us an extraordinarily intimate, compassionate and sometimes frighte ning understanding of his vocation. - The New York Times Shortlisted for both the Guardian First Book Prize and the Costa Book Award Longlisted for the Samuel Johnson Prize for Non-Fiction A Finalist for the Pol Roger Duff Cooper Prize A Finalist for the Wellcome Book Prize A Financial Times Best Book of the Year An Economist Best Book of the Year What is it like to be a brain surgeon? How does it feel to hold someone's life in your hands, to cut into the stuff that creates thought, feeling, and reason? How do you live with the consequences of performing a potentially lifesaving operation when it all goes wrong? In neurosurgery, more than in any other branch of medicine, the doctor's oath to "do no harm" holds a bitter irony. Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty. If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life. Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

From the bestselling author of Seven Brief Lessons on Physics, a concise, elegant exploration of time. Why do we remember the past and not the future? What does it mean for time to “flow”? Do we exist in time or does time exist in us? In lyric, accessible prose, Carlo Rovelli invites us to consider questions about the nature of time that continue to puzzle physicists and philosophers alike. For most readers this is unfamiliar terrain. We all experience time, but the more scientists learn about it, the more mysterious it remains. We think of it as uniform and universal, moving steadily from past to future, measured by clocks. Rovelli tears down these assumptions one by one, revealing a strange universe where at the most fundamental level time disappears. He explains how the theory of quantum gravity attempts to understand and give meaning to the resulting extreme landscape of this timeless world. Weaving together ideas from philosophy, science and literature, he suggests that our perception of the flow of time depends on our perspective, better understood starting from the structure of our brain and emotions than from the physical universe. Already a bestseller in Italy, and written with the poetic vitality that made Seven Brief Lessons on Physics so appealing, The Order of Time offers a profoundly intelligent, culturally rich, novel appreciation of the mysteries of time.

Few can imagine a world without telephones or televisions; many depend on computers and the Internet as part of daily life. Without scientific theory, these developments would not have been possible. In this exceptionally clear and engaging introduction to philosophy of science, James Ladyman explores the philosophical questions that arise when we reflect on the nature of the scientific method and the knowledge it produces. He discusses whether fundamental philosophical questions about knowledge and reality might be answered by science, and considers in detail the debate between realists and antirealists about the extent of scientific knowledge. Along the way, central topics in philosophy of science, such as the demarcation of science from non-science, induction, confirmation and falsification, the relationship between theory and observation and relativism are all addressed. Important and complex current debates over underdetermination, inference to the best explaination and the implications of radical theory change are clarified and clearly explained for those new to the subject.

What is temperature, and how can we measure it correctly? These may seem like simple questions, but the most renowned scientists struggled with them throughout the 18th and 19th centuries. In Inventing Temperature, Chang examines how scientists first created thermometers; how they measured temperature beyond the reach of standard thermometers; and how they managed to assess the reliability and accuracy of these instruments without a circular reliance on the instruments themselves. In a discussion that brings together the history of science with the philosophy of science, Chang presents the simple eet challenging epistemic and technical questions about these instruments, and the complex web of abstract philosophical issues surrounding them. Chang's book shows that many items of knowledge that we take for granted now are in fact spectacular achievements, obtained only after a great deal of innovative thinking, painstaking experiments, bold conjectures, and controversy. Lurking behind these achievements are some very important philosophical questions about how and when people accept the authority of science.