When an IMF mission ends badly, the world is faced with dire consequences. As Ethan Hunt takes it upon himself to fulfill his original briefing, the CIA begin to question his loyalty and his motives. The IMF team find themselves in a race against time, hunted by assassins while trying to prevent a global catastrophe.

With computer genius Luther Stickell at his side and a beautiful thief on his mind, agent Ethan Hunt races across Australia and Spain to stop a former IMF agent from unleashing a genetically engineered biological weapon called Chimera. This mission, should Hunt choose to accept it, plunges him into the center of an international crisis of terrifying magnitude.

Retired from active duty, and training recruits for the Impossible Mission Force, agent Ethan Hunt faces the toughest foe of his career: Owen Davian, an international broker of arms and information, who is as cunning as he is ruthless. Davian emerges to threaten Hunt and all that he holds dear -- including the woman Hunt loves.

三澄美琴（石原里美 饰）是在民间法医组织“UDI”工作的女法医，该组织专门接收由于非正常原因导致死亡的遗体，对其进行解剖以求找到案件的真相。和美琴一起工作的，还有法医中堂系（井浦新 饰）、记录员九部六郎（洼田正孝 饰）和检查技师东海林夕子（市川实日子 饰）等人。 中堂系虽然拥有着丰富的临床经验，个性却乖僻古怪，对正义和法律理解不同的美琴和中堂之间，常常产生无法调和的矛盾。其实，中堂有一个无人知晓的秘密，他的女友在一场“意外”中不幸丧生，可种种蛛丝马迹向中堂揭示了，是一名连环杀人犯取走了女友的性命。中堂不畏人言坚定的留在UDI，正是为了找到杀死女友的凶手。

利用检测杀意的系统“罔象女”搜查犯罪事件的组织，通称“仓”。 然后，神探·酒井户身为“罔象女”的操作员进入犯人的深层心理“杀意世界（井）”，对事件进行推理。 他不断追寻着频繁发生、谜团重重的凶恶事件，以及在其中若隐若现的连续杀人鬼制造者“约翰·沃克”的影子。

Investigative journalist Eddie Brock attempts a comeback following a scandal, but accidentally becomes the host of Venom, a violent, super powerful alien symbiote. Soon, he must rely on his newfound powers to protect the world from a shadowy organization looking for a symbiote of their own.