Following his great success with "North by Northwest," director Alfred Hitchcock makes a daring choice for his next project: an adaptation of Robert Bloch's novel "Psycho." When the studio refuses to back the picture, Hitchcock decides to pay for it himself in exchange for a percentage of the profits. His wife, Alma Reville, has serious reservations about the film but supports him nonetheless. Still, the production strains the couple's marriage.

When larcenous real estate clerk Marion Crane goes on the lam with a wad of cash and hopes of starting a new life, she ends up at the notorious Bates Motel, where manager Norman Bates cares for his housebound mother.