本书描述格雷诺耶自幼受苦，生有特殊的嗅觉功能，领悟惟有少女的体香能使人神魂颠倒，他先后杀死26名少女，萃取她们的体味制出神奇的香水。当他罪行败露押赴刑场时，籍以身上的异香，逃回巴黎，被流氓等分剐而食。

Jean-Baptiste Grenouille, born in the stench of 18th century Paris, develops a superior olfactory sense, which he uses to create the world's finest perfumes. However, his work takes a dark turn as he tries to preserve scents in the search for the ultimate perfume.