Following the defeat of Majin Buu, Son Goku and friends travel to Mr. Satan's newly-opened hotel for an all-you-can-eat banquet, when they are paid a visit by Vegeta's younger brother Tarble. They are informed by Tarble that the terrible brother duo of Abo and Cado have terrorized his planet and are on their way to Earth.

很久很久以前，地球上散落着七颗神奇的龙珠，传说只要聚齐它们，神龙就会出现，并可以为人实现一个愿望。为了寻找龙珠，孙悟空等人踏上了奇妙的寻珠之旅。经历了许多危险之后，终于集齐的龙珠却被抢走了。为了不让龙珠被坏蛋利用，悟空他们只好许了个无聊的愿望。神龙实现一个愿望之后，必须经过一年才会再次出现。利用这段时间，悟空去了龟仙人那里拜师学艺，而后又踏上寻找龙珠的旅程。 时光流逝……魔导师巴比迪唤醒了厉害无比的魔人布欧。人类灭绝了，超级悟天克斯、比克、还有悟饭，都被一一吸收，魔人布欧成为了全世界最厉害的人。现在，要打倒布欧，只能靠悟空了。从15代以前的界王神那里得到生命的悟空向布欧发起了挑战……