A football halfback has a heart condition, a nagging wife and a team secretary who loves him.

Jonathan Peckinpaw feels he's failed in his patriotic duty when he's rejected by the army, but he sees a chance to redeem himself by exposing a secret ring of Nazi spies.

Cookie is born, producing unmitigated joy in the Bumstead household. Adding to the chaos a new baby always creates is the appearance of Hans Conried as a cynical author who becomes caught up in the Bumstead lifestyle.

Baby Dumpling, the six-year-old son of Blondie and Dagwood Bumstead disappears from sight during his first day at school. While Dagwood frantically combs the city in search of the boy, Baby Dumpling spents a nice, safe afternoon with poor little rich girl Melinda Mason, who with her new playmate's help arises from her sickbed to walk across the room for the first time in months.

Dagwood brings home a pedigreed Great Dane which an important company client wants and which Blondie enters in the big dog show.

The Bumstead family is off to see relatives in the country when Blondie runs into Charlie and Millie, an eloping couple needing her help.

Dagwood Bumstead must receive a college diploma or lose his job with the Dithers Construction Company. Not wishing to be separated from her husband, Blondie enrolls in college as well. But Leighton College rules stipulate "No Married Couples", forcing Blondie and Dagwood to pretend that they're not married. This causes quite a dilemma when coed Laura Wadsworth begins flirting with Dagwood and Rusty Bryant does the same with Blondie. And Blondie's discovery of a very pleasant secret threatens to expose her and Dagwood's marital status too.

Dagwood wants to join the trout club and Blondie wants a fur coat. Jealousy reigns when Dag's old girlfriend Joan shows up, but nothing else matters when a drawing at the movie theatre provides money for the coat.

Mr. Dithers invites the Bumsteads on a South American cruise. Somehow Dagwood winds up as the female drummer in the ship's band, while Penny Singleton gets to show off her Broadway background in some lively musical numbers.

A cop-turned-bail bondsman gets involved in a murder investigation involving a former flame.

Legendary pirate and adventurer Sinbad is in single-minded pursuit of two things: beautiful women and a substance called Greek Fire--an early version of gunpowder.

When newlyweds visit Las Vegas, the wife's shady past comes to the surface.

Christabel fools everyone with her sweet exterior including her cousin Donna and Donna's wealthy fiancée Curtis. The only one who sees through her facade is Nick, a rugged writer who loves her anyway. Christabel also loves Nick, but she loves Curtis' money more. After convincing Curtis that Donna is only interested in him for his money, she tricks Curtis into marrying her. Of course, she still dallies with Nick on the side.