Hoping to propose to his upper-crust girlfriend, Wade Walker crashes her family's annual reunion and lands in a face-off with her dad.

Faithful wife Melinda, who is tired of standing by her devious husband Robert, is enraged when it becomes clear she has been betrayed. That's when she lost it, and now she cannot let it go.

When Shirley, Madea's niece, receives distressing news about her health, the only thing she wants is her family gathered around her. However, Shirley's three adult children are too preoccupied with their own troubled lives to pay attention to their mother. It is up to Madea, with the help of rowdy Aunt Bam, to bring the clan together and help Shirley deal with her crisis.