Polio breaks out in Rio de Janeiro, the serum is in Santiago and there's only one way to get the medicine where it's desperately needed: flown in by daring pilots who risk the treacherous weather and forbidding peaks of the Andes.

Tom Sawyer and his pal Huckleberry Finn have great adventures on the Mississippi River, pretending to be pirates, attending their own funeral and witnessing a murder.

In London, barrister Anthony Keane takes the case of Maddalena Paradine, a beautiful woman accused of poisoning her blind husband. Though happily married, Keane becomes infatuated with his enigmatic client and convinced of her innocence. His obsession clouds his judgment as he builds a defense implicating her servant, André Latour—an act that leads to devastating consequences both in court and at home.

In Imperial Russia, Anna, wife of the officer Karenin, goes to Moscow to visit her brother. On the way, she meets charming cavalry officer Vronsky, to whom she's immediately attracted. But in St. Petersburg’s high society, a relationship like this could destroy a woman’s reputation.