Deep in the Amazon, a medical mission spirals into a fight for survival when Boiúna, a colossal ancient predator, awakens to reclaim her domain. In the jungle where nature holds absolute power, she decides who lives and who dies.

Doni has lost everything. David, his best friend, is a bankrupt producer. Max is a cop who no longer believes in the law. Jack just served a five-year sentence for computer hacking. Leo has been trying to change people all his life, unsuccessfully. Inexorably, their lives cross paths…