Eve Simonswas abandoned as an infant on the steps of a church 30 years ago on Christmas Eve. Now, struggling to move forward with her life, she embarks on a search to uncover the mystery of her birth with the help of her boyfriend Chris and famed investigative genealogist Pamela Slaton.

When loser Duke, who has screwed up every hair-brained scheme he's ever come up with, accidentally falls off a cruise ship and wakes up on a mysteriously abandoned, top secret government island, he discovers that it's overrun with mutants and monsters from a failed 1980s DARPA "super soldier" project to stop the 2nd Cold War.