Missing Persons is a short-lived American crime drama television series, set in Chicago. It followed a fictitious missing persons unit; each episode usually following the investigation into three or more cases. It ran on ABC from August 30, 1993 to February 17, 1994.

It was produced by Gary Sherman Productions in association with Stephen J. Cannell Productions, and often used local Chicago-based actors, as well as occasional big-name guest stars such as Nina Foch, Eddie Bracken and Lois Smith. Semi-regulars included Ian Gomez, Irma P. Hall, Laura Cerón and Valerie Harper. Unlike most series from Cannell's company, he did not create or co-create this series.

Two Aliens visit the Earth in an effort to enlist converts to travel the universe with them.

A teenage girl becomes infatuated with a stranger who is, unbeknownst to her, a serial killer.

An unlikely Hollywood hooker helps a detective set a trap for a mutilator pimp.

When a government official disappears in the London tunnels, after several reports of missing people in the same location, Scotland Yard start to take the matter seriously, along with a couple who stumble into a victim by accident.