Documentary follows Gabriel Yorke, the actor turned Berkeley professor, who, after 25 years of silence, is finally willing to speak about his participation in the controversial film Cannibal Holocaust (1980).

Italian horror fan and academic Calum Waddell speaks with some of the original makers of the controversial horror classic "Cannibal Holocaust" before venturing into the Amazon jungle and surrounding city port, Leticia, to uncover some of the local stories behind the making of the motion picture. What is uncovered, however, leads to a wider and unexpected "true crime" story.

A New York University professor returns from a rescue mission to the Amazon rainforest with the footage shot by a lost team of documentarians who were making a film about the area's local cannibal tribes.