It's 1876 and all the Indians are at peace except the Comanches lead by Black Cloud. When Black Cloud wipes out a town, only six soldiers are left and they head for the nearest fort. In the desert they are reinforced by members of a stagecoach and find some water at a deserted mission. Pinned down by Black Cloud they send an Indian boy who was Black Cloud's prisoner on to the fort while they try to bargain with Black Cloud whom they learn is without water.

A railroad investigator discovers that there's more than meets the eye to a series of reported Indian attacks against the railroad.

A Confederate troop, led by Captain Lafe Barstow, is prowling the far ranges of California and Nevada in a last desperate attempt to build up an army in the West for the faltering Confederacy. Because the patrol saves a stagecoach, with Johanna Carterr as one of the passengers, from an Indian attack, and is marooned on a rocky mountain, it fails in its mission but the honor of the Old South is upheld.

A San Francisco hood is rubbed out by rival Bruno Felkin, who himself reports the crime to Homicide Lt. Kelsey in an alibi scheme which fails. To escape, he stows away on a fishing boat. At sea, skipper Hamil Linder receives Bruno kindly, teaching him fishing; Bruno enlists Hamil's wayward son Carl to tend his slot machines. Then Carl takes an interest in Bruno's girl Connie. Climax in a storm at sea.

Kittridge is hired by the villans but turns to defend the rancher Saxon after learning the true situation. Kittrige wins Saxon's ranch with a cut of the cards but Saxon has other reasons for loosing the gamble. Telford and Lake try everything from bushwacking to setting a wildfire to stop the Saxon/Kittridge herd of cattle from reaching the railhead.

A murderous thief on the run with stolen loot forces a poor rancher to guide him across the desert into Mexico. Accompanying them is the rancher's wife, who happens to be the killer's former girlfriend.