A man named Seligman finds a fainted wounded woman in an alley and he brings her home. She tells him that her name is Joe and that she is nymphomaniac. Joe tells her life and sexual experiences with hundreds of men since she was a young teenager while Seligman tells about his hobbies, such as fly fishing, reading about Fibonacci numbers or listening to organ music.

故事发生在六十年代中期的澳大利亚，丹尼（诺亚·泰勒 Noah Taylor 饰）是一个个性腼腆，只知道死读书的书呆子男孩，而赛迪维（桑迪·牛顿 Thandie Newton 饰）则在丹尼所就读的男校的对面女校念书，因缘际会之下，丹尼爱上了赛迪维，一段浪漫的感情即将拉开序幕。可是，在这个节骨眼上，赛迪维的家乡乌干达发生了动乱，放不下在那里生活的弟弟妹妹们的赛迪维决定返回家乡。
临别之时，丹尼和赛迪维相约在一间汽车旅馆里互诉衷肠，哪知道两人的计划被学校里的老师们发现了，在校风异常严谨刻板的当时，这种事情是绝对不会被允许的。

Arrogant, self-centered movie director Guido Contini finds himself struggling to find meaning, purpose, and a script for his latest film endeavor. With only a week left before shooting begins, he desperately searches for answers and inspiration from his wife, his mistress, his muse, and his mother.