阿信原是杀道会的成员之一，却因不明原因被杀道会下达追杀令，导致自己几乎死亡，其爱人也遭受牵连而丧命。大难不死的阿信决定复仇，而在复仇的过程中，也使得真相逐渐浮出台面。
其后，另一组织黑日军团现身，并带来新的阴谋。杀道会挺身与之对抗，使得阿信亦被卷入其中。然而，经过一番苦战之后，黑日军团依然达到其目的，造成世界各地的原有势力被重新洗牌，新的世纪就此展开……

为争夺统治权，幕府与天帝家两大势力在巨大都市天府展开了明争暗斗，而机巧技术的出现让双方的争斗更加白热化。
幕府密探田坂甚内受命调查隐居天府郊外的机巧师钉宫久藏，发现久藏与三十年前的一起倒幕事件有密切关联，而和久藏生活在一起的少女“伊武”竟是与真人无异的机巧人偶。机巧之术能制造出精致的机关器械甚至宛如活物的鸟兽，然而却无人知晓本应没有灵魂的机巧人偶为何能如人一般思考、行动，如人一般拥有喜怒哀乐。多方打探后，甚内意识到一切线索都指向天帝家代代秘传的“神代之神器”。
甚内远赴京城展开调查，试图揭开这个尘封已久的秘密。与此同时，蛰伏许久的天帝家也开始了行动……

ナチス政権下のドイツ。血のつながっていない両親とのどかに暮らしていた少年フランツ・ノインは、ある日突然ナチスの襲撃を受ける。ナチスは密かにヒトラーの血を持つ13人の子供をつくり、ドイツ各地で育てていたのだが、何らかの理由で彼らの抹殺を決めたらしい。ノインを密かに警護する命を受けていたテオ・ベッカーは、ナチスを裏切り、ノインと旅に出た。

The story unfolds in Nazi Germany, when SS Reichsführer Heinrich Himmler commanded a top secret mission in Wewelsburg under the Führer. It follows Neun, the ninth child to carry Hitler's DNA, and his protector, Teo Baker, as they travel across the country on the run from the Nazis.

Quicksilver is the story of Daniel Waterhouse, fearless thinker and conflicted Puritan, pursuing knowledge in the company of the greatest minds of Baroque-era Europe, in a chaotic world where reason wars with the bloody ambitions of the mighty, and where catastrophe, natural or otherwise, can alter the political landscape overnight. It is a chronicle of the breathtaking exploits of "Half-Cocked Jack" Shaftoe -- London street urchin turned swashbuckling adventurer and legendary King of the Vagabonds -- risking life and limb for fortune and love while slowly maddening from the pox. And it is the tale of Eliza, rescued by Jack from a Turkish harem to become spy, confidante, and pawn of royals in order to reinvent Europe through the newborn power of finance. A gloriously rich, entertaining, and endlessly inventive novel that brings a remarkable age and its momentous events to vivid life, Quicksilver is an extraordinary achievement from one of the most original and important literary talents of our time. And it's just the beginning ...